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About the project

The Digital Slide Archive (DSA) is an open-source platform for storing, managing, visualizing, and annotating large microscopy images, with a focus on whole-slide digital pathology. It is built from Girder, large_image, HistomicsUI, Slicer CLI Web, and HistomicsTK. See What is DSA? for how the pieces fit together and System overview for the deployment model.

History

The project builds on the Cancer Digital Slide Archive (CDSA), a public site that hosts whole-slide images associated with The Cancer Genome Atlas (TCGA). At more than 10,000 images and 20 terabytes, the CDSA supported TCGA Analysis Working Group studies and other investigator-driven work. DSA packages that experience as software that any lab can run for its own data. The success stories describe both efforts.

License

The Digital Slide Archive is released under the Apache License, Version 2.0.

Funding

This work was funded in part by NIH grant U24-CA194362-01.

Community

Collaborators

Organization Contributor Role
Feinberg School of Medicine, Northwestern University Lee A.D. Cooper, PhD HistomicsTK lead
Emory University School of Medicine David A. Gutman, MD, PhD Digital Slide Archive lead
Kitware, Inc. David Manthey Software engineering and deployment

Roles and affiliations are reproduced from the upstream project website on 2026-11-01; confirm current details with the project before quoting them.

How to cite

If you use DSA in published work, cite:

Gutman, David A., Mohammed Khalilia, Sanghoon Lee, Michael Nalisnik, Zach Mullen, Jonathan Beezley, Deepak R. Chittajallu, David Manthey, and Lee A.D. Cooper. “The Digital Slide Archive: A Software Platform for Management, Integration, and Analysis of Histology for Cancer Research.” Cancer Research 77, no. 21 (October 31, 2017): e75–78. doi:10.1158/0008-5472.CAN-17-0629

More references are on the papers and publications page.

This documentation site

This site is maintained in Gutman-Lab/dsa-docs. It is a consolidation area: some pages replicate material that still lives upstream, and SOURCES.md records where each page came from. The upstream project website remains https://digitalslidearchive.github.io/digital_slide_archive/.